All may not be well for the Fred Thompson presidential campaign exploratory committee testing-the-waters committee. Perhaps the news that another key aide has just quit, coupled with yesterday’s replacement of would-be campaign manager Tom Collamore with former Energy Secretary Spencer Abraham, is a sign of things NOT to come.

J.T. Mastranadi was hired just a week and a half ago to be the campaign’s director of research. He resigned this morning, a friend of his said. The friend said that Mastranadi was “fed up” with the “lack of structure” and was unclear about his role in the coming campaign.

Thompson’s spokesperson, Linda Rozett, confirmed that Mastranadi submitted his resignation this morning. “He did it for personal reasons,” she said.

Mastranadi was a former NRSC research director and is considered one of the best investigators in the business. Most recently, he worked with Thompson friend David Bossie on an anti-Hillary Clinton documentary. [MARC AMBINDER - The Atlantic]

The rumor is that Thompson’s wife Jeri may be behind the recent activity.